| 2 |
Indiana Lyons | 11/6/2021 | 5:00 PM | | nc21-22 | 101 | 111 | L |
| 6 |
Midwest Falcons | 11/13/2021 | 4:27 PM | Northside Christian | nc21-22 | 123 | 94 | W |
| 11 |
Illinois Bulldogs | 11/14/2021 | 10:55 PM | Northside Christian | nc21-22 | 154 | 108 | W |
| 16 |
Beaver County Indians | 11/20/2021 | 11:32 PM | Northside Christian | nc21-22 | 153 | 118 | W |
| 21 |
Akron Aviators | 11/27/2021 | 11:52 PM | Northside Christian | nc21-22 | 139 | 131 | W |
| 23 |
Burning River Buckets | 11/28/2021 | 11:19 PM | Northside Christian | nc21-22 | 110 | 102 | W |
| 25 |
NapTown Pros | 12/4/2021 | 5:00 PM | Northside Christian | | 156 | 129 | W |
| 39 |
Indiana Lyons | 12/12/2021 | 11:27 PM | Northside Christian | nc21-22 | 127 | 104 | W |
| 41 |
Chicago Rebels | 12/18/2021 | 12:56 AM | Northside Christian | nc21-22 | 121 | 112 | W |
| 49 |
Ohio Kings | 1/8/2022 | 6:00 PM | | nc21-22 | 120 | 119 | W |
| 76 |
Ohio Kings | 1/23/2022 | 11:22 PM | Northside Christian | nc21-22 | 147 | 100 | W |
| 70 |
Akron Aviators | 1/22/2022 | 7:02 PM | TBA | nc21-22 | 175 | 125 | W |
| 91 |
Burning River Buckets | 2/5/2022 | 3:02 AM | | nc21-22 | 128 | 114 | W |
| 60 |
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Steel City Yellow Jackets (Pitt) | 1/15/2022 | 7:55 PM | | nc21-22 | 121 | 126 | L |
| 103 |
Ohio Kings | 2/19/2022 | 5:30 PM | Northside Christian | nc21-22 | 138 | 118 | W |
| 113 |
Steel City Yellow Jackets (Pitt) | 2/26/2022 | 5:30 PM | Northside Christian | nc21-22 | 136 | 125 | W |
| 119 |
Midwest Falcons | 03/06/2022 | 5:30PM | Northside Christian | nc21-22 | 149 | 106 | W |
